UWR
UWR, The Faculty of Chemistry University of Wroclaw (www.chem.uni.wroc.pl) is the leading research institute in the field of coordination chemistry in Poland. The Faculty belongs to Wroclaw Centre for Biotechnology (WCB) Consortium that in 2014 has received the status of the Leading National Research Centre (KNOW), granted by the Polish Ministry of Science and Higher Education, in the fields of Biological Sciences, Agricultural Sciences and Earth Sciences. WCB is so far the largest consortium which has been given the status of KNOW. The interdisciplinary nature of WCB consortium allows performing comprehensive research in the field of biotechnology, chemistry, immunology and biomedicine, medicine and veterinary medicine, and the science of food and nutrition.
UWR team, the Bioinorganic and Biomedical Chemistry Group, has an impressive experience in biological inorganic chemistry, especially in the description of structure and function of biomolecules (e.g. amino acids, peptides and their phosphonic, oximic and hydroxamic analogues; nucleic acids and their subunits, nucleosides; siderophores) and their interactions with metal ions, impact of metal ions on chemistry and biochemistry of drugs, bioinorganic chemistry of toxic metals (Ni, Cd, Pb, Cr, Al ect.), molecular mechanisms of metals’ toxicity, mechanisms of neurodegeneration, and design of chelating agents for metal ions for various purposes.
Infrastructure: UWR participant is well equipped with various state-of-art devices covering nearly all experimental techniques applied in modern coordination chemistry (http://www.chem.uni.wroc.pl/Faculty_Laboratories). A variety of facilities such as ESI mass spectrometry, CD, EPR, and UV-Vis absorption spectroscopies, electrochemistry (potentiometry, cyclic voltammetry), isothermal titration calorimetry (ITC), allow studying thermodynamic and structural aspects of considered systems.
Researchers involved in the realization of the project: 2 ER, 3 ESR.
